Process Analytical Technology
Interpreting analytical signals to understand cells and the culture process.
We study process analytical technology (PAT) for measuring biomass and the culture environment. Spectroscopic analysis, process sensors and soft sensors provide complementary information for process understanding and inputs to bioprocess digital twins.
WHY IT MATTERS
Understanding changes during culture provides the basis for consistent process operation and informed control.
Research directions
- Biomass and culture-state analysis
- Spectroscopy, process sensors and soft sensors
- Data integration and state estimation