KO

CFD & Hydrodynamics

Analyzing mixing, shear and mass transfer to inform bioreactor design and process transfer.

Comparison of velocity, shear stress and energy dissipation across culture vessels and agitation conditions
Comparison of velocity, shear stress and energy dissipation across culture vessels and agitation conditionsKim et al. (2025), Biotechnology and Bioprocess EngineeringView original image ↗

We connect computational fluid dynamics (CFD) with cell-culture performance. Hydrodynamic analysis of shaking flasks and stirred bioreactors informs design, scale-up and transfer across reactor geometries and scales.

CFD analysis from the publication

Ryu et al. (2026), Figure 3: hydrodynamic characteristics of STR 2 L and STR 10 L

Ryu et al. (2026), Fig. 3 · Applied Microbiology and Biotechnology · CC BY 4.0

WHY IT MATTERS

Comparing reactor environments identifies hydrodynamic conditions that matter during process transfer.

Research directions

  • CFD analysis of flow, mixing and shear
  • Shaking-flask and stirred-bioreactor characterization
  • Bioreactor design, scale-up and process transfer
← All core technologies